Shirleen started her nursing career in 1982 at the LAC/USC School of Nursing diploma program. She then completed the RN-to-BSN program at California State University in Fullerton. Ms. Chase and her family moved to Tennessee where she attended the University of Tennessee in Chattanooga in the Clinical Nurse Specialist track with additional course work to obtain a Certificate of Fitness to practice as a Nurse Practitioner in Tennessee. She has continued practicing as either a Clinical Nurse Specialist or Nurse Practitioner since graduation. Recently she completed her PhD in Nursing from the University of Tennessee in Knoxville and a  Post-Master’s Nursing Education Certificate program. Prior to moving to Chattanooga, she practiced as an APRN with orthopedic and surgical oncology services at Vanderbilt University in Nashville. There she worked closely with experts in solid tumor and cutaneous malignancies, caring for cancer survivors.

Shirleen has also spent time developing alternative learning opportunities in undergraduate and graduate nursing programs that appeal to a new generation of students in addition to new teaching strategies. Her educational research interests include specialty advanced practice nurse mentoring, online learning, and clinical decision-making. She has expertise in teaching at a distance and served as content expert along with coordinating nursing specific media at Laureate Education for Walden University’s MSN program. Dr. Chase's skills include curriculum development, course writing, along with educational media production. The production team she was part of won two educational media awards for work on two MSN core nursing courses, ‘Understanding Healthcare Systems’ (Videographer Award of Excellence) and ‘Linking Theory with Nursing Practice’ (Award of Distinction). Dr. Chase has been involved with committee work at UTC and in the SON along with membership in several national nursing and research organizations. She has also been an officer in the local chapter of nursing's national honor society.

Shirleen Chase's clinical program of research includes cancer survivorship, supportive care, and survivorship program outcomes. With over 33 years of experience in healthcare and nursing, her career thus far spans a variety of settings including critical care, oncology, administration, research, education, and advanced practice. She has also developed a manual for faculty teaching online and has several manuscripts in development for publication. She was also recognized with a 2016 CHEPS Outstanding Teaching/Advising Award at UTC. Dr. Chase has presented locally, regionally, and nationally.