Shirleen started her nursing career in 1982 at the LAC/USC School of Nursing diploma program. She then completed the RN-to-BSN program at California State University in Fullerton. Ms. Chase and her family moved to Tennessee where she attended the University of Tennessee in Chattanooga in the Clinical Nurse Specialist track with additional course work to obtain a Certificate of Fitness to practice as a Nurse Practitioner in Tennessee. She has continued practicing as either a Clinical Nurse Specialist or Nurse Practitioner since graduation. Currently, she is a candidate for a PhD in Nursing from the University of Tennessee in Knoxville and recently completed the Post Master’s Nursing Education Certificate program at UT. In addition to teaching full time at the University of Tennessee at Chattanooga SON, she practice as an APRN at the Center for Digestive Care and Management in Chattanooga. Prior to moving to Chattanooga, she practiced as an APRN with orthopedic and surgical oncology services at Vanderbilt in Nashville. There she worked closely with experts in solid tumor and cutaneous malignancies, caring for patients across the spectrum of care in both the inpatient and outpatient environments.

Shirleen has also spent time developing alternative learning opportunities in undergraduate and graduate nursing programs that appeal to a new generation of students in addition to new teaching strategies. Her educational research interests include specialty advanced practice nurse mentoring, simulation learning, and clinical decision-making. Additionally, she teaches in the Nurse Practitioner program in the SON. She has expertise in teaching at a distance and served a content expert along with coordinating nursing specific media for Laureate Education for Walden University’s MSN program. Ms Chase's skills include curriculum development, course writing, along with production and post-production skills. The MSN program core courses followed CCNE accreditation guidelines and ANCC standards for graduate nursing programs along with clinical expertise from ANCC Magnet Certified health care facilities. The production team she was part of won two educational media awards for work on two MSN core nursing courses, ‘Understanding Healthcare Systems’ (Videographer Award of Excellence) and ‘Linking Theory with Nursing Practice’ (Award of Distinction). Shirleen has been involved with committee work at UTC and in the SON along with membership in several national nursing and research organizations. She has also been an officer in the local chapter of nursing's national honor society.

Shirleen Chase's clinical program of research includes cancer survivorship posttreatment, symptom management, chronic illness impact on quality-of-life, and research methodologies. With over 33 years of experience in healthcare and nursing, her career thus far spans a variety of settings including critical care, adult health, perioperative, oncology nursing, administration, research, education, and advanced practice. She has also developed a manual for faculty teaching online and has several manuscripts in development for publication. She was also recognized with a 2016 CHEPS Outstanding Teaching/Advising Award at UTC. Shirleen has presented locally, regionally, and nationally.