Spring 2016 Seminar Schedule

*All seminars are held in Grote 411 at 3 p.m., unless otherwise indicated.

Following the seminar, the speaker will be available for comments and questions.

Date

Speaker

Title

February 12, 2016

David Shenberger - Arcade Beauty

The Art and Science of Fragrance and Cosmetic Sampling in a Changing Global Market 

February 26, 2016 

Mark Dadmun - UTK

Understanding the Science of Superglue Fuming to Improve the Quality of Developed Latent Prints

March 11, 2016

Ronghu Wu - Georgia Tech

Systematic and Quantitative Study of Human Cell Surface Glycoproteins

April 1, 2016

Brett Taubman - Appalachian State University

coming soon

April 8, 2016 

 

 

 

Abstracts

David Shenberger, Manager R&D/Regulatory, Arcade Beauty, Chattanooga, TN, "The Art and Science of Fragrance and Cosmetic Sampling in a Changing Global Market"

Many likely have experienced fragrance through the decades old technology of ScentStrip®, paper samplers that you snap open to release a scent, or Microfragrance™ better known as Scratch ‘n’ Sniff.  Both rely on microencapsulation to contain, protect, and stabilize the fragrance and the art of formulation to obtain the desired olfactory rendition that equates to a retail product.  We will discuss in detail common encapsulation reactions such as simple and complex coacervation, and polymer condensation then broadly explore a variety of other methods, the importance of release mechanisms, and some of the numerous magical products that rely on encapsulation. 

We will take an interactive look at a variety of fragrance and cosmetic sampling technologies highlighting some of the chemical challenges to overcome with application or dispensing, product stability, material compatibility, and ultimately desired function.

Finally we will explore the forces driving innovation in the chemical, cosmetic, and fragrance industry such as evolving global regulations, pressure from NGOs (Non-Governmental Organizations), and the shift from traditional marketing to electronic marketing.

 

Mark Dadmun, UTK, "Understanding the Science of Superglue Fuming to Improve the Quality of Developed Latent Prints"

In this lecture, recent work that has examined the growth process of cyanoacrylate polymer chains that occurs during the superglue fuming of latent fingerprints will be discussed.  Results from our lab indicate that the primary initiators of the polymerization of cyanoacrylate from latent prints are the carboxylate groups in sodium lactate or amino acids of the print. Additionally, in many forensic investigations, the latent print is often exposed to the environment before it is obtained.  The quality of an aged print that is developed by superglue fuming is often inferior to those from fresh prints, presumably due to changes in the print composition with environmental exposure. Methods to improve the quality of aged prints that have been developed based on our fundamental understanding of the polymerization process of cyanoacrylate during fuming of prints will be presented. Our recent research in this area focuses on the role of fuming temperature on the ability of initiators in the print to grow poly(ethyl cyanoacrylate) during fuming.  These results show that an optimal temperature for fuming is ~ 10°C and provides a molecular level explanation for the temperature dependence. The goal of these experiments is to provide insight into the molecular level processes that occur during the fuming process, information that will enable the development of laboratory procedures to control and potentially speed up this practice.

 

Ronghu Wu, Georgia Tech, "Systematic and Quantitative Study of Human Cell Surface Glycoproteins"

Glycoproteins on the cell surface are ubiquitous and essential for human cells to interact with the extracellular matrix, communicate with other cells, and respond to environmental cues. Although surface glycoproteins can dramatically impact cell properties and represent different cellular statuses, global and site-specific analysis of glycoproteins only on the cell surface is extraordinarily challenging. In our lab we have developed innovative and effective mass spectrometry-based methods to globally analyze surface glycoproteins. Surface glycoproteins metabolically labeled with a functional group were specifically tagged through click chemistry, which is ideal because it is quick, specific and occurs under physiological conditions. Sequentially tagged glycoproteins were enriched for site-specific identification by mass spectrometry. Systematic and quantitative analysis of the surface N-glycoproteome in cancer cells with distinctive invasiveness demonstrated many N-glycoproteins up-regulated in highly invasive cells, the majority of which contained cell adhesion-related domains. Cell surface glycoprotein dynamics has also been investigated and their half-lives been accurately measured. Considering the importance of surface glycoproteins, the newly developed methods will have extensive applications in the biological and biomedical research communities.

 

Brett Taubman, Appalachian State University, ""

coming soon